Adrianne Palicki
Supernaturalrole:Palicki first appeared in the pilot as Jess, Sam’s college girlfriend.
Over the years, she’d star in four episodes total.
She’s since starred onAgents of S.H.I.E.L.D.,The Orville, and more.
Sergei Bachlakov /The CW
Best known for:Milligan is now best known for playing Ted onSchitt’s Creek.
Lauren Cohan
Supernaturalrole:Cohan played Bela Talbot on sixSupernaturalepisodes in 2007 and 2008.
Best known for:Avgeropoulos is now known for playing Octavia Blake onThe 100.
Sergei Bachlakov /The CW
(Spoiler: The ghost turned out to be a real girl.)
Best known for:Benson spent seven years playing Hanna Marin on the Freeform hitPretty Little Liars.
Best known for:Since then, Spiridakos is known for her work onRevolutionandChicago P.D.
The CW
Best known for:Monteith memorably played Finn Hudson on the Fox hitGlee, which premiered in 2009.
Tragically, he died of an accidental overdose in 2013.
Katie Cassidy
Supernaturalrole:Cassidy had a recurring arc as the original Ruby duringSupernatural’s third season.
The CW
Best known for:Now Cassidy is best known for her work on another CW show:Arrow.
Best known for:King is now known for playing Caroline Forbes on eight seasons ofThe Vampire Diaries.
Best known for:Dier is now most recognizable for playing Michael Cordero Jr. onJane the Virgin.
Michael Courtney/The CW
Madison McLaughlin
Supernaturalrole:Beginning in 2012, McLauglin played Krissy Chambers in two episodes ofSupernatural.
Best known for:McLaughlin went on to have roles onChicago P.D.andArrow.
Sergei Bachlakov /The CW
The CW
Michael Courtney/The CW
Sergei Bachlakov /The CW
Sergei Bachlakov/The CW
Sergei Bachlakov /The CW
The CW
The CW
The CW
Sergei Bachlakov /The CW
The CW
Michael Courtney/The CW
The CW
The CW
The CW
The CW
Jack Rowand/The CW
The CW
Katie Yu/The CW
