The celebrated star played P.J.
The actress played Dr. Ellis Grey in a 2010 flashback episode, depicting Meredith’s mother during her residency.
He visits the hospital after getting attacked by a lion belonging to his girlfriend.
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Rita Moreno
Rita Morenobrought her star power toGrey’sin the 12th season.
She portrayed Gayle, a woman visiting her cheating husband in the hospital.
Lowes played an unnamed blood donor.
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She played the daughter of a woman with a delicate condition who becomes obsessed with her mother’s care.
He played Jake Burton, a patient with a unique condition that makes him look like a lion.
Keke Palmer
Keke Palmerpicked up a one-episode gig onGrey’s Anatomyin 2014.
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Her character was one of the hospital’s first powerhouse surgeons who returns for a procedure.
She played a patient undergoing a liver transplant.
Kurt Fuller
Kurt Fulleradded to his extensive filmography in 2007 with an episode ofGrey’s Anatomy.
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He played Jerry, a patient with an extensive run of bad luck.
Annie Potts
Veteran starAnnie Pottsdropped in onGrey’s Anatomy’s 10th season in 2013.
She played Joyce Bosco, a woman at the hospital with her husband.
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Ethan Embry
Ethan Embryappeared in a 2012 episode ofGrey’sas Dr. David Moore.
He played a doctor who worked with Arizona after the loss of her leg.
She played Courtney Hall, a pregnant patient who chats with the doctors about their taxes.
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Weil played Allison Clark, a cancer patient who bonds with Izzie.
She would later return to Shondaland as Bonnie Winterbottom onHow to Get Away with Murder.
Mary Pat Gleason
Mary Pat Gleasonfound a spot in a 2013 episode ofGrey’s Anatomy.
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The veteran actress played Marge Walker, a patient with one gnarly infection.
Jamie Chung
In 2010,Jamie Chungguest-starred onGrey’s Anatomyas Trina Paiz.
She found herself in the hospital after falling and cutting her ear.
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Natalie Cole
Famed performerNatalie Coleappeared in a 2006 episode ofGrey’s Anatomy.
She appeared as a therapist who works with Callie and Arizona.
Mary Lynn Rajskub
Mary Lynn Rajskubappeared in an episode ofGrey’s Anatomyin 2012.
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The24actress portrayed Marion Steiner, a woman who contracts a parasite after traveling abroad.
He plays a man who visits the hospital with his hypochondriac wife.
Sara Gilbert
Sara Gilbertplayed a character named Kim Allen in a 2010 episode ofGrey’s Anatomy.
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Jurnee Smollett
Jurnee Smollettpicked up a two-episode arc onGrey’s Anatomyin 2008.
Lee Majors
Lee Majorsmade his appearance onGrey’s Anatomyin 2011.
Audra McDonald
Amid herPrivate Practicerun,Audra McDonaldstopped byGrey’s Anatomyas Dr. Naomi Bennett.
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Ernie Hudson
Ernie Hudsonmade an appearance in one 2011 episode ofGrey’s Anatomy.
She played a little girl who bonds with Alex over her inability to feel pain.
The teenager is bitter over her seemingly dire condition, but gets new hope thanks to Izzie.
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Mandy Moore
Mandy Mooredid a four-episode stint onGrey’s Anatomyin 2010.
TheThis Is Usactress played a woman named Mary Portman.
Bernadette Peters
Bernadette PetersjoinedGrey’s Anatomyfor two episodes in 2008.
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Veronica Cartwright
Veronica Cartwrightappeared as Lydia Ashford in two episodes ofGrey’s Anatomyin 2013.
She plays a patient in the hospital worried about her house’s state after a violent storm.
Christina Ricci
Christina Riccihit the small screen in 2006 for two tense episodes ofGrey’s Anatomy.
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He played a soldier working on getting in fighting condition to return to the battlefield.
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