The actress' children shared the news on her social media account.

EW has confirmed news of her death.

As iconic as she was on screen, she was an even more amazing mother and grandmother."

Ted Danson and Kirstie Alley on ‘Cheers’

Ted Danson and Kirstie Alley on ‘Cheers’.NBC/Everett

For the part, Alley received five Emmy nominations, winning once in 1991.

More recently, she starred in the 2013 filmSyrupand the 2015 David O. Russell filmAccidental Love.

Alley was born January 12, 1951 in Wichita, Kansas.

TO TELL THE TRUTH - “Anna Camp, Joel McHale, Ron Funches, Kirstie Alley” - Anna Camp, Joel McHale, Ron Funches and Kirstie Alley make up the celebrity panel on “To Tell the Truth,” airing SUNDAY, JUNE 30 (10:00-11:00 p.m. EDT), on The ABC Television Network, streaming and on demand. The panel is presented with a variety of participants with interesting stories, from a record-breaking bubble artist to the inventor of PopSockets® and a voodoo practitioner. (Eric McCandless/ABC via Getty Images) KIRSTIE ALLEY

Kirstie Alley.Eric McCandless/ABC via Getty

She leaves behind her children True and Lillie, and grandson Waylon.